منابع مشابه
Pneumoviruses: Molecular Genetics and Reverse Genetics
Pneumoviruses are responsible for significant respiratory disease in their hosts and represent a major problemfor human and animal health. Pneumoviruses are members of the family Paramyxoviridae, subfamilyPneumovirinae and the virus particles consist of a negative-sense, nonsegmented RNA genome within a helical nucleocapsid structure enveloped in a lipid membrane derived from the ho...
متن کاملMolecular genetics of primary congenital glaucoma in Brazil.
PURPOSE To determine the distribution of CYP1B1 gene mutations in Brazilian patients with primary congenital glaucoma (PCG). METHODS PCG diagnosis was established by presence of buphthalmos in at least one affected eye and associated high intraocular pressures before the age of 3 years. CYP1B1 mutation screening of 52 patients with PCG was performed by SSCP and direct sequencing of PCR fragme...
متن کاملAdult-onset primary glaucoma and molecular genetics: a review.
PURPOSE To evaluate recent molecular genetic studies focused on localizing and identifying the genes involved in adult-onset primary glaucoma, characterizing the gene products, and investigating the molecular mechanisms implicated in the pathophysiology of the disease. METHODS Several studies have aimed at understanding gene expression and protein processing and attempting to correlate the mu...
متن کاملMolecular Genetics and Epidemiology of Vitiligo
Background: Vitiligo is an acquired, idiopathic, and common depigmentation disorder of the skin that affects people of all ages and both sexes equally in the worldwide. Although etiology of the disease is unknown, there are theories such as environment and genetic factors. Methods: In this article, we collected and summarized the appropriate manuscripts regarding the epidemiology and gene...
متن کاملGenetics of closed-angle glaucoma.
Acute inflammatory or congestive glaucoma was recognized in ancient times as an entity and well it might be in view of its dramatic symptoms and extreme pain. In 1857 von Graefe described its symptomatology in modem language and recognized it as a primary form of glaucoma in the adult. Among other features he noted that a characteristic of the eye so affected was shallowness of the anterior cha...
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ژورنال
عنوان ژورنال: Experimental Eye Research
سال: 2011
ISSN: 0014-4835
DOI: 10.1016/j.exer.2011.08.007